MIRDct

 

The (freely available) MIRDct software has been developed as a community tool for performing organ-level CT dosimetry. It facilitates dose estimations using a precomputed Monte Carlo-based dose library, accommodating a range of CT scanner models, collimation settings, kVp options, and tube current modulation (TCM) features. MIRDct incorporates an extensive library of 24 ICRP mesh-type phantoms spanning various ages, body habitus, and both sexes, with over 40 predefined organs and regions for dose evaluation. The software supports user-defined scan protocols, rapid calculation of organ doses, effective dose, and risk indices, and offers visualization and quality control functionalities for enhanced clinical and educational use.

More information can be found in the software manual.

FAQ

• MIRDct is freely available for download
• MIRDct is written/compiled in the Mircosoft Excel platform
• Features of MIRDct: dose coefficient database, flexible CT protocol selection, tube current modulation (TCM) modeling, integration with mesh-type phantoms, graphical user interface, dose uncertainty propagation, and visual output for dose distribution and organ-specific metrics
• Future versions are expected

Reference Publications

MIRD Pamphlet No. 34, Part 1: MIRDct-A Customizable Software Tool for CT Dosimetry.

Ocampo Ramos JC, Kofler C, Dawson R, Baggett J, Dinwiddie LE, Domal SJ, Carter LM, Marquis H, Kayal G, Zanzonico PB, Bolch WE, Kesner AL.  J Nucl Med. 2026 Apr 1;67(4):651-660. doi: 10.2967/jnumed.125.270494. PMID: 41679920; PMCID: PMC13041616.

https://doi.org/10.2967/jnumed.125.270494 

MIRD Pamphlet No. 34, Part 2: Benchmarking of MIRDct Software for CT Organ Dose Estimation. 

Kayal G, Ocampo Ramos JC, Dinwiddie LE, Baggett JM, Dawson RJ, Marquis H, Wehmeier SK, Ivashchenko O, Carter LM, Bolch WE, Kesner AL. J Nucl Med. 2026 Sep 2;67(9):1491-1502. doi: 10.2967/jnumed.125.271501. PMID: 42315308; PMCID: PMC13544246.

https://doi.org/10.2967/jnumed.125.271501

Documentation & Instruction Manuals

Document manual (version 1.0.0.0)

System Requirements

MIRDct is written and compiled within Microsoft Excel, and runs in the Excel environment. A licensed version of Microsoft Excel must be installed on the host computer.

Currently, MIRDct has only been developed to work on a PC.

Acknowledgements & Authors

The MIRDct software is a product of an ongoing collaboration between University of Florida, Gainesville, FL, USA and Memorial Sloan Kettering Cancer Center, New York, USA.

This research was part of a funded project support by the NIH U01 EB028234 grant.

Major contributors to this development of this software include: 

Juan C. Ocampo Ramos (MSKCC)

Adam L. Kesner (MSKCC), Lukas M. Carter (MSKCC), Harry Marquis (MSKCC), Gunjan Kayal (MSKCC), Pat B. Zanzonico (MSKCC), Cameron Kofler(UF), Sean J. Domal(UF), Robert Dawson(UF), Jared Baggett(UF), Laura E. Dinwiddie (UF), Wesley E. Bolch(UF)